Help take care of osteoporosis SME research scientist to prove the efficacy of vitamin E oil

Osteoporosis is a degenerative disease that causes bones to become lime, brittle, and easily broken.
Among the main causes of the disease is the lack of female sex hormone estrogen that is applicable when a person the woman starts menopause or menopos (menopause).
The same thing also applies to the male sex hormone that is deficient testosterone. The disease is also applicable as a result of the aging process initially finished.
However, an investigator from Universiti Kebangsaan Malaysia (UKM), Prof. Dr. Ima Nirwana Soelaiman prevail found levels of vitamin E in the oil head can help nurture and strengthen its original brittle bones due to osteoporosis.
Clearly Dr. Ima Nirvana, osteoporosis apply if it were the original bone absorption levels not matched by levels of bone formation.
"In other words erties levels applicable pereputan faster bone formation versus bone originally.
"This imbalance would lead to bone wedges, quickly broken or fragile," he said when met after delivering the inaugural professor syarahan entitled tocotrienol: Vitamin E Oil for treating osteoporosis in the mother country recently.
Added Dr. Ima Nirvana, among other factors the enactment of the disease termasuklah excess steroid hormones and thyroid hormone deficiency plus calcium and vitamin D.
Indeed, to cope with the disease, taking vitamin E was encouraged because the fat soluble vitamins famous for their antioxidant characteristics.
"Vitamin E than the oil terbahagi to two large sets namely tocopherols and tocotrienols that are detailed to the four isomers.
"Between both, a tocotrienol antioxidant agent with power of 50-fold more potent compared to a-tocopherol," he said.
That respect, one typical study has been conducted regarding the impression of vitamin E, especially tocotrienol up bone metabolism and osteoporosis.
Study chaired by Dr. Ima Nirvana is to prove tocotrienols than the original plant so as palm oil has the potential to be developed as an agent antiosteoporosis.
"Additional now palm oil is the country's main commodities found to have a high content of tocotrienols, the material is precisely selected to be commercialized," he said.
Results of a study conducted to find tocotrienols memorable in the process of increasing bone ketumpatan mice tested in the lab.
In the study conducted, the rats were tested will be given the various pressures that led to the pereputan micro-architecture of bone.
In addition the study Dr. Ima Nirwana also found that tocotrienols also help improve ketumpatan normal bone osteoporosis stage.
Nevertheless, before something original material so it can be used as ubatan, these materials need to be assessed scientifically.
There are several studies that need to be implemented ratings for ensuring the material is safely used as ubatan.
The rating is a study in vivo (environments, True) against animals, studies in vitro (test environments) to the cell culture system, the study of the toxicity of the material to the animal and clinical studies on humans.
In vivo studies on animals aimed at ensuring THAT materials studied have a beneficial impression upon the disease being studied.
In vitro studies on cell cultures to also get to know the definite mechanism of reprisals against specific cells.
Ketoksidan study also usually done by giving high dos-dos to the animals in a period of time specified.
The study goal was to get to know a side and Kesa definite impression that if there are toxic materials.
The third-ranked three studies is recognized as praklinikal study and after the study to all victorious, baharulah studies on man will be implemented.
However, clinical studies on humans are not easy and need to go through several phases before implementation justified.
Overall these studies prove the bone strength is increasing along with the addition ketumpatannya after being treated using tocotrienols.
"The study also showed tocotrienols safety profile to be used safely, termasuklah when pregnant.
"After further studies on humans are still not able to be implemented berikutan funding restraints," he said.

Vitamin E than other types of tocotrienol memorable to prevent and help treat osteoporosis due to various factors such as sex hormone deficiency, oxidative stress, nicotine, as well as the abuse of medicine.
Tocotrienol was also impressive increase bone density and strength normal once gus prevent the entry into force of osteoporosis in the future.
The study also found tocotrienols work to prevent the entry into force of the complications of osteoporosis, namely pereputan bones (fractures) to improve bone strength and endurance against the load.
May be used as food additives, tocotrienols help speed up the healing fractures due to osteoporosis.
When asked when would tocotrienol product on the market, Dr. Ima Nirwana said, upon human clinical studies need to be done first before the product is marketed.
However, the study will take a period of four to five years longer berikutan shortage of suitable infrastructure required in addition to boarding a bit high.
"If there are agencies or those interested in this clinical study may be shortened and this product will meet the customers so that they can live a better life," he said.